Increased microvascular flow and foot sensation with mild continuous external compression

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Increased microvascular flow and foot sensation with mild continuous external compression

Intermittent pneumatic compression of the calf and foot increases inflow to the popliteal artery and skin. We hypothesize that mild, continuous pneumatic compression of the lower extremities of type 2 diabetic patients increases microvascular blood flow to skin (SBF) and muscle (MBF) and improves sensation in feet. Data were collected on 19 healthy volunteers and 16 type 2 diabetic patients. Ba...

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Increased cardiac output and microvascular blood flow during mild hemoconcentration in hamster window model.

The effect of small hematocrit (Hct) increases on cardiac index (cardiac output/body wt) and oxygen release to the microcirculation was investigated in the awake hamster window chamber model by means of exchange transfusions of homologous packed red blood cells. Increasing Hct between 8 and 13% from baseline increased cardiac index by 5-31% from baseline (P < 0.05) and significantly lowered sys...

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Enhancing sensation in diabetic neuropathic foot with mechanical noise.

OBJECTIVE Localized low-level mechanical or electrical noise can significantly enhance tactile sensitivity in healthy young subjects and older adults. This phenomenon is termed stochastic resonance (SR). In this study, we examined the effect of SR on vibratory and tactile sensation in patients with moderate to severe diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS A total of 20 su...

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ژورنال

عنوان ژورنال: Physiological Reports

سال: 2013

ISSN: 2051-817X

DOI: 10.1002/phy2.157